Bovine dermatosparaxis: presumptive clinical and pathological diagnosis of an outbreak in Argentina
DOI:
https://doi.org/10.63207/ai.v8i15.168Keywords:
dermatosparaxis, bovine, ArgentinaAbstract
Dermatosparaxis is an inherited autosomal recessive disorder of connective tissue. We describe the clinical and pathological findings with dermal lesions characterized by thin, loose skin that was easily detached, affecting three out of 45 calves, in a 100 red Aberdeen Angus cows. Histopathological findings were consistent with dermatosparaxis, characterized by loss and disorder of the collagenous substance of the dermis. Anamnesis suggested that the semen used from a red Aberdeen Angus bull, which could carried the genetic alteration in these cases. This is the first description of a clinical disease compatible with dermatosparaxis in red Aberdeen Angus cattle in Argentina.
Downloads
References
Carty, C., Lee, A., Wienandt, N., Stevens, E., Alves, D., Browne, J., Bryan, J., Ryan, E., Cassidy, J. (2016). Dermatosparaxis in two Limousin calves. Irish Veterinary Journal. 69: 15. Disponible en: https://doi.org/10.1186/s13620-016-0074-5
Colige, A., Sieron, A., Li, S., Schwarze, U., Petty, E., Wertelecki, W., Wilcox, W., Krakow, D., Cohn, D., Reardon, W., Byers, P., Lapie`re, C., Prockop, D., Nusgens, B. (1999). Human Ehlers-Danlos syndrome type VII C and Bovine dermatosparaxis are caused by mutations in the Procollagen I N-Proteinase gene. The American Journal of Human Genetics, 65:308–317
Dalir-Naghadeh, B., Seifi, H.A. and Farshid, A.A. (2004). Congenital Bovine Epitheliogenesis Imperfecta: A Report of Three Cases from Iran. Journal of Veterinary Medicine Series A. 51: 409-412. Disponible en: https://doi.org/10.1111/j.1439-0442.2004.00670.x
Halper, J. (2014). Trastornos del tejido conectivo en animales domésticos. En: Halper, J. (eds) Progreso en enfermedades hereditarias del tejido conectivo blando. Avances en medicina y biología experimental, vol. 802. Springer, Dordrecht. Disponible en: https://doi.org/10.1007/978-94-007-7893-1_14
Holm, D., van Wilpeb, E., Harperc, C., Duncand, N. (2008). The occurrence of dermatosparaxis in a commercial Drakensberger cattle herd in South Africa. Journal of the South African Veterinary Association. 79 (1): 19-24.
Jolly, R., Alley, M., O’Hara, P. (1973). Familial acantholysis of Angus calves. Veterinary Pathology. 10 (6):473-483. doi: 10.1177/030098587301000601
Jubb, Kennedy y Palmer. (2007). Pathology of Domestic Animals. 5ta ed. Edited M Gant Maxie. Saunders Elsevier. ISBN 13-978070202784-0. 588-590.
Machado, M., Cardozo, E., Artigas, R., Verdes, J. (2022). Descripción de un caso clínico compatible con dermatosparaxis (síndrome de Elhers-Danlos tipo VIIc) en un ternero cruza charolais con hereford. Veterinaria (Montevideo), 58:218, e403. Disponible en: https://doi.org/10.29155/vet.58.218.4
Medeiros, G. & Riet-Correa, F. (2015). Epidermolysis bullosa in animals: a review. Vet Dermatol. 26: 3-e2. Disponible en: https://doi.org/10.1111/vde.12176.
Muñoz, M., García Pariente, C., Pérez Pérez, V., Fuertes, Franco, M., Camarena, M. T., Delgado, L., García Marín, JF., Ferreras, MC. (2008). Descripción de dos casos compatibles con dermatosparaxis en bovinos. XX Reunión de la Sociedad Española de Anatomía Patológica Veterinaria (SEAPV). 18-20 junio 2008, Los Cancajos, Breña Baja (La Palma), España, 63.
NORD (National Organization for Rare Disorders). 2021. Síndromes de Ehlers-Danlos September 27. Disponible en: https://rarediseases.org/es/rare-diseases/sindromes-de-ehlers-danlos/
-Piérard, G., Hermanns-Lê, T., Arrese-Estrada, J., Piérard-Franchimont, C., Lapière, C. 1993. Structure of the Dermis in Type VIIC Ehlers—Danlos Syndrome. The American Journal of Dermatopathology. 15 (2):127-132.
Van Leuven, J. (1987). Heritable collagen dysplasia in domestic animals and man: a comparative review. Vlaams Diergeneeskundig Tijdschrift, 56 (2): 89-99.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Ab Intus
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
