Phenolic compounds and inhibition of oxidative stress of a methanolic extract of avocado seed (Persea americana Mill).
Abstract
Persea americana Mill, or simply avocado is one of the fruits with
the highest content of biactive compounds, where its seed, considered a waste
product, has a high antioxidant potential that can generate health benefits. The
objective of the study was to determine the concentration of total phenolic
compounds, flavonoids and to evaluate the antioxidant activity of an methanolic
extract of avocado seeds. An extract was prepared using 70% methanol and
one claimed that it served exclusively to buy the content of total phenols and
flavonoids. The Folin-Ciocalteu method, the colorimolic method proposed by
Marinova, and the oxidative stress test in Saccharomyces cerevisiae (biological
model) were used. The analysis showed a concentration of total phenols of 53.12
± 1.35 and flavonoids 38.22 ± 0.69 with statistical difference with the extract
used as control. In relation to the antioxidant activity, inhibition of the oxidative
stress induced in S. cerevisiae was observed by the extract. From being a waste
material, these results indicate that the avocado seed can be an alternative for
the consumption of bioactive compounds, which coincides with those reported
worldwide.
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