Determinación de la sobrevida en perras con neoplasias mamarias sometidas a mastectomía

  • Marina Caffaratti Departamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
  • Griselda González Departamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto
  • Guillermo Bagnis Departamento de Patología Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
  • Corina Guendulain Departamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
  • Pablo González Departamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
  • Aníbal Bessone Departamento de Clínica Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.

Resumen

Las neoplasias mamarias caninas son un motivo de consulta muy frecuente en la clínica veterinaria de pequeños animales y su tratamiento de elección es la mastectomía. Establecer el pronóstico de esta patología es uno de los aspectos fundamentales de la práctica médica y resulta de mucho interés para los propietarios. El objetivo del presente trabajo fue determinar la sobrevida libre de enfermedad (SLE) y la sobrevida general (SG) de las perras sometidas a mastectomía como único tratamiento de esta neoplasia y su relación con las características histopatológicas. Fueron incluidas 22 perras que presentaron masas compatibles con neoplasias mamarias sometidas a mastectomía. Luego se realizó el diagnostico histopatológico de las lesiones y el seguimiento de las perras durante 24 meses, con  controles trimestrales en búsqueda de recidiva local o metástasis. Se analizaron los resultados y se determinó que el 50% de los tumores fueron benignos y 50% malignos. El período de SLE promedio fue de 318 días y de 436 días para la SG. Se encontró asociación entre el tipo histológico y el pronóstico de la enfermedad: los carcinomas simples y mixtos tuvieron un comportamiento menos agresivo que otros carcinomas. También, se observó relación entre la SLE y la SG con el grado histológico de malignidad, a menor grado, mayor SG; siendo en este caso estadísticamente significativa.


 


Survival determination of bitches with mammary neoplasias subjected to mastectomy 


Abstract. Canine mammary neoplasm is a very frequent reason for clinical consultation and its treatment of choice is mastectomy. In medical practice, one of the fundamental aspects is determine the prognostic of this pathology and this is an issue of interest to the owners. The aim of this work was to determine the disease free survival (DFS) and the overall survival (OS) of the bitches subjected to mastectomy as the only treatment of this neoplasm and its relationship, with histolopathological characteristics. Twenty-two bitches that presented masses compatible with mammary neoplasms subjected to mastectomy were included in this research. Then, the histopathological diagnosed of the lesions and the clinical follow-up during 24 months was carried out. The bitches were controlled quarterly after surgery in search of local recurrence or distant metastases. The results were analyzed and it was determined that 50% were benign tumors and 50% were malignant tumors. The average DFS period was 318 days and the mean OS was 436 days. An association between the histological type and the prognosis of the disease was found: simple and mixed carcinomas had a less aggressive behavior than other carcinomas. Furthermore, there was a relationship between DFS and OS with the tumor malignancy grade, at a lower grade, greater OS; in this last case it was significantly statistically.

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Publicado
2020-07-29
##submission.howToCite##
CAFFARATTI, Marina et al. Determinación de la sobrevida en perras con neoplasias mamarias sometidas a mastectomía. Ab Intus, [S.l.], v. 3, n. 5, p. 19-29, july 2020. ISSN 2618-2734. Disponible en: <http://www.ayv.unrc.edu.ar/ojs/index.php/Ab_Intus/article/view/127>. Fecha de acceso: 28 sep. 2020
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